Chromatography represents the most versatile separation technique and is readily available. At the early stage of drug discovery, many closely related compounds are synthesized and are required to be separated. Their identification and purity testing are very essential. Chromatography techniques are widely used for these applications. Chromatography instruments have applications in the separation, purification, and analysis of raw materials, Active Pharmaceutical Ingredients (APIs), and excipients. Thus, the growing requirements for high-quality drugs and implementation of stringent government initiatives are increasing the demand of chromatography resin in several countries.
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Synthetic resins segment is projected to register the highest CAGR between 2022 and 2027. The demand for synthetic resins is expected to be driven by their use in ion-exchange chromatography. Polystyrene divinylbenzene is the most commonly used synthetic resin, which is increasingly used in IEX technique because of its better performance characteristics in comparison to natural polymers. The growth of the synthetic resins segment is projected to be driven by its increasing use in analytical or laboratory-scale applications.
Affinity was the largest chromatography technique in 2021 in terms of value
The affinity chromatography technique is based on the selective affinity of molecules in the mobile phase toward ligands coupled to the stationary resin. The rising demand for protein A for convenient and efficient antibody purification is expected to drive the affinity chromatography segment. Affinity chromatography offers high selectivity, resolution, and capacity in most protein purification schemes. It has the advantage of utilizing a protein’s biological structure or function for purification. All these factors drive the demand for affinity technique
North America accounted for the largest share of the global chromatography resin market, in terms of both volume and value, in 2021. The US is the leading market for chromatography resin in North America, followed by Canada. A strong therapeutic monoclonal antibody market in North America is one of the key drivers for chromatography resin market. Modern chromatographic techniques are also increasingly used in food analytics and other diagnostic purposes in the US as well as in Canada. Most of the key pharmaceutical companies have their research centers in North America. All these factor drive the demand for chromatography resin in North America.
The chromatography resin market is donimated by a few globally established players such as Danaher Corporation (US), Bio-Rad Laboratories Inc. (US), Merck KGaA (Germany), Tosoh Corporation (Japan), BioWorks Technologies AB (Sweden), Kaneka Corporation (Japan), Avantor Performance Materials, Inc (US), Purolite Corporation (US), Repligen Corporation (US), AND Thermo Fisher Scientific Inc. (US).
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